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Article

Erythropoietic differentiation of a human embryonic stem cell line harbouring the sickle cell anaemia mutation.

Reproductive biomedicine online - 1 Aug 2010

Pryzhkova Marina V, Peters Ann, Zambidis Elias T

Abstract excerpt

Herein is reported efficient erythropoietic differentiation of a human embryonic stem cell (ESC) line derived from a preimplantation genetic diagnosis (PGD)-screened embryo that harbours the homozygous sickle cell disease (SCD) haemoglobinopathy mutation. This human ESC line possesses typical pluripotency characteristics and forms multilineage teratomas in vivo. SCD-human ESC efficiently differentiated to the...

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Source

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Identifiers

PMID: 20541472
DOI: 10.1016/j.rbmo.2010.04.017
PMCID: PMC3507446

Genes

PGD
SCD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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