Article
Rab-mediated vesicular transport is required for neuronal positioning in the developing Drosophila visual system.
Molecular brain - 11 Jun 2010
Houalla Tarek, Shi Lei, van Meyel Donald J, Rao Yong
Abstract excerpt
BACKGROUND: The establishment of tissue architecture in the nervous system requires the proper migration and positioning of newly born neurons during embryonic development. Defects in nuclear translocation, a key process in neuronal positioning, are associated with brain diseases such as lissencephaly in humans. Accumulated evidence suggests that the molecular mechanisms controlling neuronal movement are...
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