Article
The guanine exchange factor vav controls axon growth and guidance during Drosophila development.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 10 Feb 2010
Malartre Marianne, Ayaz Derya, Amador Fatima Fernandez, Martín-Bermudo Maria Dolores
Abstract excerpt
The Vav proteins are guanine exchange factors (GEFs) that trigger the activation of the Rho GTPases in general and the Rac family in particular. While the role of the mammalian vav genes has been extensively studied in the hematopoietic system and the immune response, there is little information...
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