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Article

Immune Activation in Retinal Aging: A Gene Expression Study

11 Jun 2010

Abstract excerpt

PURPOSE: To investigate changes in gene expression during aging of the retina in the mouse. METHODS: Total RNA was extracted from the neuroretina of young (3-month-old) and old (20-month-old) mice and processed for microarray analysis. Age-related, differentially expressed genes were assessed by the empiric Bayes shrinkage-moderated t-statistics METHOD: Statistical significance was based on dual criteria of a...

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PMID: 20538981
DOI: 10.1167/iovs.09-5103

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