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Article

The associations of Janus kinase-2 (JAK2) A830G polymorphism and the treatment outcomes in patients with acute myeloid leukemia.

Leukemia & lymphoma - 1 Jun 2010

Zhong Yuejiao, Chen Baoan, Feng Jifeng, Cheng Lu, Li Yufeng, Qian Jun, Ding Jiahua, Gao Feng, Xia Guohua, Chen Ningna, Lu Zuhong

Abstract excerpt

The Janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway is active in both normal hematopoiesis and hematological malignancies. Moreover, Janus kinase-2 (JAK2) is the key hematopoietic kinase, and mutations together with single nucleotide polymorphisms (SNPs) of JAK2 have been thoroughly evaluated. In this study, we aimed to investigate whether the synonymous genetic polymorphism A830G...

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Identifiers

PMID: 20536350
DOI: 10.3109/10428191003774960

Genes

JAK2

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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