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Article

Metabolic engineering of Klebsiella pneumoniae and in silico investigation for enhanced 2,3-butanediol production.

Biotechnology letters - 1 Jun 2016

Rathnasingh Chelladurai, Park Jong Myoung, Kim Duk-Ki, Song Hyohak, Chang Yong Keun

Abstract excerpt

OBJECTIVES: To improve the production of 2,3-butanediol (2,3-BD) in Klebsiella pneumoniae, the genes related to the formation of lactic acid, ethanol, and acetic acid were eliminated. RESULTS: Although the cell growth and 2,3-BD production rates of the K. pneumoniae ΔldhA ΔadhE Δpta-ackA strain were lower than those of the wild-type strain, the mutant produced a higher titer of 2,3-BD and a higher yield in batch...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26886192
DOI: 10.1007/s10529-016-2062-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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