Article
Impaired cell surface expression of HLA-B antigens on mesenchymal stem cells and muscle cell progenitors.
PloS one - 28 May 2010
Isa Adiba, Nehlin Jan O, Sabir Hardee J, Andersen Tom E, Gaster Michael, Kassem Moustapha, Barington Torben
Abstract excerpt
HLA class-I expression is weak in embryonic stem cells but increases rapidly during lineage progression. It is unknown whether all three classical HLA class-I antigens follow the same developmental program. In the present study, we investigated allele-specific expression of HLA-A, -B, and -C at the mRNA and protein levels on human mesenchymal stem cells from bone marrow and adipose tissue as well as striated...
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