Article
Association of Disrupted in Schizophrenia 1 (DISC1) missense variants with ultra-resistant schizophrenia.
The pharmacogenomics journal - 1 Aug 2011
Mouaffak F, Kebir O, Chayet M, Tordjman S, Vacheron M N, Millet B, Jaafari N, Bellon A, Olié J P, Krebs M-O
Abstract excerpt
Three common missense variants of the Disrupted in Schizophrenia 1 (DISC1) gene, rs3738401 (Q264R), rs6675281 (L607F) and rs821616 (S704C), have been variably associated with the risk of schizophrenia. In a case-control study, we examine whether these gene variants are associated with schizophrenia and ultra-resistant schizophrenia (URS) in a population of French Caucasian patients. The URS phenotype is...
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