Article
Selection of genes and single nucleotide polymorphisms for fine mapping starting from a broad linkage region.
Twin research and human genetics : the official journal of the International Society for Twin Studies - 1 Dec 2007
Windelinckx An, Vlietinck Robert, Aerssens Jeroen, Beunen Gaston, Thomis Martine A I
Abstract excerpt
Fine mapping of linkage peaks is one of the great challenges facing researchers who try to identify genes and genetic variants responsible for the variation in a certain trait or complex disease. Once the trait is linked to a certain chromosomal region, most studies use a candidate gene approach...
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