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Article

Dynamics of lamin-A processing following precursor accumulation.

PloS one - 28 May 2010

Liu Qian, Kim Dae In, Syme Janet, LuValle Phyllis, Burke Brian, Roux Kyle J

Abstract excerpt

Lamin A (LaA) is a component of the nuclear lamina, an intermediate filament meshwork that underlies the inner nuclear membrane (INM) of the nuclear envelope (NE). Newly synthesized prelamin A (PreA) undergoes extensive processing involving C-terminal farnesylation followed by proteolysis yieldin...

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Identifiers

PMID: 20526372
DOI: 10.1371/journal.pone.0010874
PMCID: PMC2878336

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20526372-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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