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Article

Nonallelism for the audiogenic seizure prone (Asp1) and the aryl hydrocarbon receptor (Ahr) loci in mice.

Journal of neurogenetics - 1 Nov 1998

DiRocco L, Dalton T, Liang D, Nebert D W, Seyfried T N

Abstract excerpt

Previous studies showed an association between the Ahr locus on Chr 12 and a major gene, Asp1, that influences susceptibility to audiogenic seizures (AGS) in mice. Although the association was thought to involve close linkage, a pleiotropic effect of the Ahr locus on AGS susceptibility was not excluded. Two congenic strains, D2.B6N-Asp1b and the D2N.B6N-Ahrb1, were used to evaluate further the association between...

Topics

Alleles
Animals
Chromosome Mapping
Chromosomes, Human, Pair 12
Epilepsy, Reflex
Genetic Predisposition to Disease
Humans
Mice
Mice, Congenic
Polymerase Chain Reaction
Receptors, Aryl Hydrocarbon

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 10656108
DOI: 10.3109/01677069809108558

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