Article
Functional anatomy of the murine sinus node: high-resolution optical mapping of ankyrin-B heterozygous mice.
American journal of physiology. Heart and circulatory physiology - 1 Aug 2010
Glukhov Alexey V, Fedorov Vadim V, Anderson Mark E, Mohler Peter J, Efimov Igor R
Abstract excerpt
The mouse is widely used as a genetic platform to investigate the molecular mechanisms of sinoatrial node (SAN) pacemaking. Recently, it has been shown that isolated SAN cells from the ankyrin-B (AnkB)-deficient mice display severe pacemaking dysfunction similar to individuals harboring ankyrin 2...
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