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Article

Chromosome mosaicism in day 3 aneuploid embryos that develop to morphologically normal blastocysts in vitro

1 Aug 2000

Abstract excerpt

In all, 143 human embryos obtained 3 days (day 3) after insemination or intracytoplasmic sperm injection (ICSI) were biopsied and a single nucleated cell removed for identification of aneuploidy by fluorescent in-situ hybridization (FISH) for chromosomes X, Y, 13, 16, 18 and 21. Fifty-one per cent of embryos were aneuploid and significantly more aneuploid embryos blocked in further development to morulae and...

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Identifiers

PMID: 10920103
DOI: 10.1093/humrep/15.8.1781

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