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Increased gene expression of diacylglycerol kinase eta in bipolar disorder

2 Jun 2010

Abstract excerpt

Bipolar disorder (BD) is a highly heritable neuropsychiatric illness characterized by recurrent episodes of depression and mania or hypomania. Recent genome-wide association studies of BD have proposed novel candidates, including the gene encoding the η isoform of diacylglycerol kinase (DGKH; Baum et al. 2008 a). The association of this gene with BD was replicated at the haplotype level in a Sardinian sample...

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PMID: 20519059
DOI: 10.1017/s1461145710000593

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