Article
Effect of variation in diacylglycerol kinase η (DGKH) gene on brain function in a cohort at familial risk of bipolar disorder.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Mar 2012
Whalley Heather C, Papmeyer Martina, Romaniuk Liana, Johnstone Eve C, Hall Jeremy, Lawrie Stephen M, Sussmann Jessika E, McIntosh Andrew M
Abstract excerpt
Several lines of evidence indicate that the diacylglycerol kinase eta (DGKH) gene is implicated in the etiology of bipolar disorder (BD). However, the functional neural mechanisms of DGKH's risk association remain unknown. Therefore, we examined the effects of three haplotype-tagging risk variants in DGKH (single nucleotide polymorphisms rs9315885, rs1012053, and rs1170191) on brain activation using a verbal...
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