Article
Polymorphisms in the TNF-α and IL-10 gene promoters and risk of psoriasis and correlation with disease severity.
Cytokine - 1 Apr 2014
Karam Rehab A, Zidan Haidy E, Khater Mohamed Hamed
Abstract excerpt
Several cytokines were assumed to play an essential role in the induction and the pathogenesis of psoriasis. The aim of this work was to investigate the role of TNF-α-308 and IL-10-1082 polymorphisms and their serum levels in the pathogenesis of psoriasis and determine their relation to disease severity. 110 Psoriasis patients and 120 healthy volunteers were genotyped for TNF-α-308 and IL-10-1082 polymorphism by...
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