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Article

Molecular genesis of drug-resistant and vaccine-escape HBV mutants.

Antiviral therapy - 1 Jan 2010

Locarnini Stephen A, Yuen Lilly

Abstract excerpt

A high rate of viral turnover, combined with an error-prone polymerase, results in a very high frequency of mutational events during HBV replication. Not surprisingly, particular selection pressures, both endogenous (host immune clearance) and exogenous (vaccines and antivirals), readily select o...

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Identifiers

PMID: 20516565
DOI: 10.3851/IMP1499

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20516565-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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