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Article

The correlation pattern of acquired copy number changes in 164 ETV6/RUNX1-positive childhood acute lymphoblastic leukemias.

Human molecular genetics - 15 Aug 2010

Lilljebjörn Henrik, Soneson Charlotte, Andersson Anna, Heldrup Jesper, Behrendtz Mikael, Kawamata Norihiko, Ogawa Seishi, Koeffler H Phillip, Mitelman Felix, Johansson Bertil, Fontes Magnus, Fioretos Thoas

Abstract excerpt

The ETV6/RUNX1 fusion gene, present in 25% of B-lineage childhood acute lymphoblastic leukemia (ALL), is thought to represent an initiating event, which requires additional genetic changes for leukemia development. To identify additional genetic alterations, 24 ETV6/RUNX1-positive ALLs were analyzed using 500K single nucleotide polymorphism arrays. The results were combined with previously published data sets,...

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Source

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Identifiers

PMID: 20513752
DOI: 10.1093/hmg/ddq224
PMCID: PMC3146010

Genes

ETV6
RUNX1
PAX5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The correlation pattern of acquired copy number changes in 164 ETV6/RUNX1-positive childhood acute lymphoblastic leukemias.PMID 20513752Read ↗

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