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Article

ETV6-RUNX1 fusion gene and additional genetic changes in infant leukemia: a genome-wide analysis.

Cancer genetics and cytogenetics - 1 Sept 2009

Emerenciano Mariana, Bungaro Silvia, Cazzaniga Giovanni, Dorea Maria Dolores Fonseca, Coser Virginia Maria, Magalhães Isis Quezado, Biondi Andrea, Pombo-de-Oliveira Maria S

Abstract excerpt

Acute lymphoblastic leukemia (ALL) in infants is characterized by a high frequency of MLL gene rearrangements. By contrast, the t(12;21) ETV6-RUNX1 fusion gene is typically detected in children older than 2 years. In a series of Brazilian infant leukemia cases, however, four younger cases harbored ETV6-RUNX1, at ages 2, 3, 5, and 7 months. This finding could represent a unique model for delineating the additional...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Core Binding Factor Alpha 2 Subunit

Share to Gene Fusion

Share to Genome-Wide Association Study

Share to In Situ Hybridization, Fluorescence

Share to Oncogene Proteins, Fusion

Share to Precursor Cell Lymphoblastic Leukemia-Lymphoma

Source

Identifiers

PMID: 19665068
DOI: 10.1016/j.cancergencyto.2009.04.021

Genes

ETV6
RUNX1
MTAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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ETV6-RUNX1 fusion gene and additional genetic changes in infant leukemia: a genome-wide analysis.PMID 19665068Read ↗

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