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Article

Leveraging human genetics to develop future therapeutic strategies in rheumatoid arthritis.

Rheumatic diseases clinics of North America - 1 May 2010

Plenge Robert M, Raychaudhuri Soumya

Abstract excerpt

The purpose of this article is to place these genetic discoveries in the context of current and future therapeutic strategies for patients with RA. More specifically, this article focuses on (1) a brief overview of genetic studies, (2) human genetics as an approach to identify the Achilles heel of disease pathways, (3) humans as the model organism for functional studies of human mutations, (4) pharmacogenetic...

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Identifiers

PMID: 20510233
DOI: 10.1016/j.rdc.2010.03.002
PMCID: PMC2879392

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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