Article
An FcgammaRIIb transmembrane polymorphism in Chinese ITP patients.
Platelets - 1 Jan 2010
Xu Jianhui, Huang Ying, Tao Jie, Zhou Zeping, Chen Zhenping, Ge Jing, Yang Renchi
Abstract excerpt
Immune thrombocytopenic purpura (ITP) is putatively associated with self-antibodies against platelet. FcgammaRIIb is a key regulator of B cell responses. To explore the relationship between the polymorphism of FcgammaRIIb transmembrane portion and ITP, a cohort control study was carried out. Two hundred and eighty ITP patients and 243 healthy volunteers were enrolled in this study. Most of the ITP patients were...
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