Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genomic alterations reveal potential for higher grade transformation in follicular lymphoma and confirm parallel evolution of tumor cell clones.

Blood - 2 Sept 2010

Eide Marianne Brodtkorb, Liestøl Knut, Lingjaerde Ole Christian, Hystad Marit E, Kresse Stine H, Meza-Zepeda Leonardo, Myklebost Ola, Trøen Gunhild, Aamot Hege Vangstein, Holte Harald, Smeland Erlend Bremertun, Delabie Jan

Abstract excerpt

Our aim was to examine the genetics of clonal evolution in follicular lymphoma (FL) and to identify genetic alterations associated with disease progression. A total of 100 biopsies from 44 patients diagnosed with t(14;18)-positive FL were examined by array comparative genomic hybridization. In 20 patients the patterns of somatic hypermutations (SHMs) in the variable region of heavy chain gene were additionally...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Human, Pair 2
Share to Chromosomes, Human, Pair 3

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 5

Share to Comparative Genomic Hybridization

Share to Immunoglobulin Heavy Chains

Share to Immunoglobulin Variable Region

Share to Lymphoma, Follicular

Share to Lymphoma, Large B-Cell, Diffuse

Source

Identifiers

PMID: 20505157
DOI: 10.1182/blood-2010-03-272278

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genomic alterations reveal potential for higher grade transformation in follicular lymphoma and confirm parallel evolution of tumor cell clones.PMID 20505157Read ↗

Clonal Evolution in t(14;18)-Positive Follicular Lymphoma, Evidence for Multiple Common Pathways, and Frequent Parallel Clonal EvolutionSemantic proximity Read ↗

Prognostic significance of secondary cytogenetic alterations in follicular lymphomasSemantic proximity Read ↗

Dynamic changes in clonal architecture during disease progression in follicular lymphomaSemantic proximity Read ↗

Analysis of secondary chromosomal alterations in 165 cases of follicular lymphoma with t(14;18)Semantic proximity Read ↗

Increasing genomic and epigenomic complexity in the clonal evolution from in situ to manifest t(14;18)-positive follicular lymphomaSemantic proximity Read ↗

Identification of cytogenetic subgroups and karyotypic pathways of clonal evolution in follicular lymphomasSemantic proximity Read ↗

Histological Transformation and Progression in Follicular Lymphoma: A Clonal Evolution Study.Semantic proximity Read ↗

Genetic evolution of in situ follicular neoplasia to aggressive B-cell lymphoma of germinal center subtypeSemantic proximity Read ↗

High Throughput Sequencing Analysis of the Immunoglobulin Heavy Chain Gene from Flow-Sorted B Cell Sub-Populations Define the Dynamics of Follicular Lymphoma Clonal Evolution.Semantic proximity Read ↗

Molecular Ontogeny of Donor-Derived Follicular Lymphomas Occurring after Hematopoietic Cell TransplantationSemantic proximity Read ↗

Transformation of follicular lymphoma to diffuse large cell lymphoma is associated with a heterogeneous set of DNA copy number and gene expression alterationsSemantic proximity Read ↗

Genome-wide profiling of follicular lymphoma by array comparative genomic hybridization reveals prognostically significant DNA copy number imbalancesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.