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Article

A systems biology approach to dissection of the effects of small bicyclic peptidomimetics on a panel of saccharomyces cerevisiae mutants.

The Journal of biological chemistry - 23 Jul 2010

Stefanini Irene, Trabocchi Andrea, Marchi Emmanuela, Guarna Antonio, Cavalieri Duccio

Abstract excerpt

In recent years, an approach called "chemical genetics" has been adopted in drug research to discover and validate new targets and to identify and optimize leads by high throughput screening. In this work, we tested the ability of a library of small peptidomimetics to induce phenotypic effects wi...

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Identifiers

PMID: 20501664
DOI: 10.1074/jbc.M110.125153
PMCID: PMC2906338

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HAP1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20501664-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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