Structural organization of the multifunctional animal fatty-acid synthase.

doi:10.1111/j.1432-1033.1991.tb16052.x

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Article

Structural organization of the multifunctional animal fatty-acid synthase.

European journal of biochemistry - 15 Jun 1991

Witkowski A, Rangan V S, Randhawa Z I, Amy C M, Smith S

Abstract excerpt

The amino acid sequence of the multifunctional fatty-acid synthase has been examined to investigate the exact location of the seven functional domains. Good agreement in predicting the location of interdomain boundaries was obtained using three independent methods. First, the sites of limited proteolytic attack that give rise to relatively stable, large polypeptide fragments were identified; cryptic sites for...

Topics

Alcohol Dehydrogenase
Amino Acid Sequence
Animals
Chickens
Cloning, Molecular
Endopeptidases
Enoyl-(Acyl-Carrier-Protein) Reductase (NADH)
Escherichia coli
Fatty Acid Synthases
Gene Library
Horses

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Macromolecular Substances

Models, Structural

Molecular Sequence Data

Mutation

Oxidoreductases

Peptide Fragments

Protein Conformation

Source

Open in PubMed

Identifiers

PMID: 2050137
DOI: 10.1111/j.1432-1033.1991.tb16052.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2050137-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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