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Article

Membrane topology of mouse stearoyl-CoA desaturase 1.

The Journal of biological chemistry - 13 Jan 2006

Man Weng Chi, Miyazaki Makoto, Chu Kiki, Ntambi James M

Abstract excerpt

Stearoyl-CoA desaturase (SCD) is an integral membrane protein anchored in the endoplasmic reticulum. It catalyzes the biosynthesis of monounsaturated fatty acids that are required for the synthesis of triglycerides, cholesteryl esters, and phospholipids. Four mouse isoforms of SCD (SCD1-4) and two human isoforms have been characterized. In the current study, we characterize the topology of the mouse SCD1 isoform....

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Source

Identifiers

PMID: 16275639
DOI: 10.1074/jbc.M508733200

Genes

SCD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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