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Article

[Global DNA hipomethylation--the meaning in carcinogenesis].

Postepy biochemii - 1 Jan 2010

Guz Jolanta, Foksiński Marek, Oliński Ryszard

Abstract excerpt

DNA methylation plays an important role in the regulation of gene expression. Tumor cells are characterized by alterations of DNA methylation pattern, namely local CpG island hypermethylation and genome wide hypomethylation. The hypomethylation of the genome affects many repetitive sequences and transposable elements and is believed to results in chromosomal instability and increased mutations events. In this...

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PMID: 20499677

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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