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Article

Cancer epigenetics: DNA methylation and chromatin alterations in human cancer.

Advances in experimental medicine and biology - 1 Jan 2003

Esteller Manel

Abstract excerpt

Aberrations in the DNA methylation patterns are nowadays recognized as a hallmark of human cancer. One of the most characteristic changes is the hypermethylation of CpG islands of tumor suppressor genes associated with their transcriptional silencing. The target genes are distributed in all cellu...

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Source

Identifiers

PMID: 12908548
DOI: 10.1007/978-1-4615-0081-0_5

Genes

BRCA1
GSTP1
MGMT
VHL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12908548-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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