Article
Further evidence supporting the association between 5HTR2C gene and bipolar disorder.
Psychiatry research - 30 Dec 2010
Mazza Marianna, Mandelli Laura, Martinotti Giovanni, Di Nicola Marco, Tavian Daniela, Negri Gloria, Colombo Elisa, Missaglia Sara, De Ronchi Diana, Colombo Roberto, Janiri Luigi, Serretti Alessandro
Abstract excerpt
Three 5HTR2C polymorphisms were investigated in bipolar (BD) spectrum disorders. The functional rs6318 G (Cys) allele was more frequent in BD patients than in controls (P=0.0036). Thus, 5HTR2C may have a role in BD. Further investigation is required to understand its involvement in co-morbidity for substance use disorders (SUDs).
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