Article
Linkage of large-vessel carotid atherosclerotic stroke to inflammatory genes via a systematic screen.
International journal of stroke : official journal of the International Stroke Society - 1 Jun 2010
Belfer Inna, Wu Tianxia, Hipp Heather, Walter Joan, Scully Michele, Nyquist Paul A, Bollettino Antonella, Goldman David, Max Mitchell B, DeGraba Thomas J
Abstract excerpt
BACKGROUND: Inflammatory cytokines including the IL-1 family, TNF-alpha and IL-6 mediate the formation of thrombosis on the luminal surface of atherosclerotic plaques. Gene polymorphisms that regulate these cytokines' expression may explain part of the variation in susceptibility to stroke in pat...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
