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Article

Prognostic role of MIR146A polymorphisms for cardiovascular events in atrial fibrillation.

Thrombosis and haemostasis - 1 Oct 2014

Roldán Vanessa, Arroyo Ana Belen, Salloum-Asfar Sallam, Manzano-Fernández Sergio, García-Barberá Nuria, Marín Francisco, Vicente Vicente, González-Conejero Rocío, Martínez Constantino

Abstract excerpt

There are few biomarkers able to forecast new thrombotic events in patients with AF. In this framework, microRNAs have emerged as critical players in cardiovascular biology. In particular, miR-146a-5p is recognised as an important negative regulator of inflammation. This study aims to evaluate the prognostic role and biological effect of functional MIR146A polymorphisms, rs2431697 and rs2910164, in non-valvular...

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PMID: 25008481
DOI: 10.1160/TH14-01-0092

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ACE

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