Article
Mutants of Candida albicans hypersensitive to calcofluor white display susceptibility to antifungal drugs.
Folia microbiologica - 1 Mar 2010
He Zhu-Mei, Chen Jing, Li Hong-Zhou, Luo Di-Qing, Yang Wei
Abstract excerpt
An increased infection incidence of Candida albicans (most common human fungal pathogen) contributes to the need of further functional genetic studies and development of new antifungal drugs. We developed a method to create mutants of C. albicans using an antisense cDNA library to interfere with gene expression, followed by screening for hypersensitivity to Calcofluor White (CFW) and the antifungal drugs...
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