Article
Sensitivity of White and Opaque Candida albicans Cells to Antifungal Drugs.
Antimicrobial agents and chemotherapy - 1 Aug 2017
Craik Veronica B, Johnson Alexander D, Lohse Matthew B
Abstract excerpt
White and opaque cells of Candida albicans have the same genome but differ in gene expression patterns, metabolic profiles, and host niche preferences. We tested whether these differences, which include the differential expression of drug transporters, resulted in different sensitivities to 27 antifungal agents. The analysis was performed in two different strain backgrounds; although there was strain-to-strain...
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