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Article

Genetic progression and the waiting time to cancer.

PLoS computational biology - 1 Nov 2007

Beerenwinkel Niko, Antal Tibor, Dingli David, Traulsen Arne, Kinzler Kenneth W, Velculescu Victor E, Vogelstein Bert, Nowak Martin A

Abstract excerpt

Cancer results from genetic alterations that disturb the normal cooperative behavior of cells. Recent high-throughput genomic studies of cancer cells have shown that the mutational landscape of cancer is complex and that individual cancers may evolve through mutations in as many as 20 different c...

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Identifiers

PMID: 17997597
DOI: 10.1371/journal.pcbi.0030225
PMCID: PMC2065895

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17997597-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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