Article
CYP2C9 and VKORC1 genotypes in Puerto Ricans: A case for admixture-matching in clinical pharmacogenetic studies.
Clinica chimica acta; international journal of clinical chemistry - 6 Sept 2010
Villagra David, Duconge Jorge, Windemuth Andreas, Cadilla Carmen L, Kocherla Mohan, Gorowski Krystyna, Bogaard Kali, Renta Jessica Y, Cruz Irelys A, Mirabal Sara, Seip Richard L, Ruaño Gualberto
Abstract excerpt
BACKGROUNDS: Admixture is of great relevance to the clinical application of pharmacogenetics and personalized medicine, but unfortunately these studies have been scarce in Puerto Ricans. Besides, allele frequencies for clinically relevant genetic markers in warfarin response (i.e., CYP2C9 and VKO...
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