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Article

Identification of ancestry proportions in admixed groups across the Americas using clinical pharmacogenomic SNP panels.

Scientific reports - 13 Jan 2021

Debortoli Guilherme, de Araujo Gilderlanio Santana, Fortes-Lima Cesar, Parra Esteban J, Suarez-Kurtz Guilherme

Abstract excerpt

We evaluated the performance of three PGx panels to estimate biogeographical ancestry: the DMET panel, and the VIP and Preemptive PGx panels described in the literature. Our analysis indicate that the three panels capture quite well the individual variation in admixture proportions observed in recently admixed populations throughout the Americas, with the Preemptive PGx and DMET panels performing better than the...

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PMID: 33441860
DOI: 10.1038/s41598-020-80389-9
PMCID: PMC7806998

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