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Article

Prevalence of combinatorial CYP2C9 and VKORC1 genotypes in Puerto Ricans: implications for warfarin management in Hispanics.

Ethnicity & disease - 1 Jan 2009

Duconge Jorge, Cadilla Carmen L, Windemuth Andreas, Kocherla Mohan, Gorowski Krystyna, Seip Richard L, Bogaard Kali, Renta Jessica Y, Piovanetti Paola, D'Agostino Darrin, Santiago-Borrero Pedro J, Ruaño Gualberto

Abstract excerpt

Polymorphisms in the cytochrome P450 2C9 (CYP2C9) and vitamin K epoxide reductase complex subunit 1 (VKORC1) genes significantly alter the effective warfarin dose. We determined the frequencies of alleles, single carriers, and double carriers of single nucleotide polymorphisms (SNPs) in the CYP2C...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20073138
PMCID: PMC2903231

Genes

VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20073138-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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