Article
Bone marrow-derived endothelial progenitor cells confer renal protection in a murine chronic renal failure model.
American journal of physiology. Renal physiology - 1 Aug 2010
Sangidorj Odongua, Yang Seung Hee, Jang Hye Ryoun, Lee Jung Pyo, Cha Ran-hui, Kim Sun Moon, Lim Chun Soo, Kim Yon Su
Abstract excerpt
Endothelial cell damage and impaired angiogenesis substantially contribute to the progression of chronic renal failure (CRF). The effect of endothelial progenitor cell (EPC) treatment on the progression of CRF is yet to be determined. We performed 5/6 nephrectomy to induce CRF in C57BL/6 mice. EPCs were isolated from bone marrow, grown in conditioned medium, and characterized with surface marker analysis. The...
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