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Article

Endothelial colony-forming cells ameliorate endothelial dysfunction via secreted factors following ischemia-reperfusion injury.

American journal of physiology. Renal physiology - 1 May 2017

Collett Jason A, Mehrotra Purvi, Crone Allison, Shelley W Christopher, Yoder Mervin C, Basile David P

Abstract excerpt

Damage to endothelial cells contributes to acute kidney injury (AKI) by leading to impaired perfusion. Endothelial colony-forming cells (ECFC) are endothelial precursor cells with high proliferative capacity, pro-angiogenic activity, and in vivo vessel forming potential. We hypothesized that ECFC may ameliorate the degree of AKI and/or promote repair of the renal vasculature following ischemia-reperfusion (I/R)....

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Identifiers

PMID: 28228404
DOI: 10.1152/ajprenal.00643.2016
PMCID: PMC5451554

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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