Article
Isolation and epithelial co-culture of mouse renal peritubular endothelial cells.
BMC cell biology - 30 Nov 2014
Zhao Ye, Zhao Hong, Zhang Yun, Tsatralis Tania, Cao Qi, Wang Ya, Wang Yiping, Wang Yuan Min, Alexander Steve I, Harris David C, Zheng Guoping
Abstract excerpt
BACKGROUND: Endothelial-mesenchymal transition (EndoMT) has been shown to be a major source of myofibroblasts, contributing to kidney fibrosis. However, in vitro study of endothelial cells often relies on culture of isolated primary endothelial cells due to the unavailability of endothelial cell lines. Our recent study suggested that peritubular endothelial cells could contribute to kidney fibrosis through...
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