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Article

Ex vivo expanded natural regulatory T cells from patients with end-stage renal disease or kidney transplantation are useful for autologous cell therapy.

Kidney international - 1 Jun 2018

Landwehr-Kenzel Sybille, Zobel Anne, Hoffmann Henrike, Landwehr Niels, Schmueck-Henneresse Michael, Schachtner Thomas, Roemhild Andy, Reinke Petra

Abstract excerpt

Novel concepts employing autologous, ex vivo expanded natural regulatory T cells (nTreg) for adoptive transfer has potential to prevent organ rejection after kidney transplantation. However, the impact of dialysis and maintenance immunosuppression on the nTreg phenotype and peripheral survival is not well understood, but essential when assessing patient eligibility. The current study investigates regulatory...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29792274
DOI: 10.1016/j.kint.2018.01.021

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Ex vivo expanded natural regulatory T cells from patients with end-stage renal disease or kidney transplantation are useful for autologous cell therapy.PMID 29792274Read ↗

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