Article
Evaluation of HLA-G5 plasmatic levels during pregnancy and relationship with the 14-bp polymorphism.
American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Nov 2010
Gonzalez Alvaro, Alegre Estibaliz, Torres Maria I, Díaz-Lagares Angel, Lorite Pedro, Palomeque Teresa, Arroyo Ainhoa
Abstract excerpt
PROBLEM: Plasmatic HLA-G levels increase during pregnancy, but the contribution of each different isoform has not been elucidated yet. METHOD OF STUDY: HLA-G5 was analyzed by ELISA in 19 controls, 79 women in the first 8 weeks of pregnancy and in nine women monthly until delivery. Genotyping for the 14-bp polymorphism was performed by PCR amplification of exon 8. RESULTS: HLA-G5 was detected in plasma from 80% of...
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