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Article

Asymmetric TDP-43 distribution in primary progressive aphasia with progranulin mutation.

Neurology - 18 May 2010

Gliebus G, Bigio E H, Gasho K, Mishra M, Caplan D, Mesulam M-M, Geula C

Abstract excerpt

OBJECTIVE: Primary progressive aphasia (PPA) results from an asymmetric degeneration of the language dominant (usually left) hemisphere and can be associated with the pathology of Alzheimer disease (AD) or frontotemporal lobar degeneration (FTLD). This study aimed to investigate whether the anatomic distribution of TDP-43 inclusions displayed a corresponding leftward asymmetry in a patient with PPA with a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20479359
DOI: 10.1212/WNL.0b013e3181df0a1b
PMCID: PMC2875132

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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