Article
An autopsy case of Alzheimer's disease presenting with primary progressive aphasia: a clinicopathological and immunohistochemical study.
Neuropathology : official journal of the Japanese Society of Neuropathology - 1 Sept 2000
Li F, Iseki E, Kato M, Adachi Y, Akagi M, Kosaka K
Abstract excerpt
This report describes an autopsied Alzheimer's disease (AD) patient with primary progressive aphasia (PPA) as an early symptom. The patient developed a progressive speech disturbance at the age of 70 years, and difficulty in comprehension became apparent 2 years later. Magnetic resonance imaging scan disclosed asymmetrical brain atrophy, predominantly on the left temporal lobe. At the age of 74 years, the...
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