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Article

Filamin a mediates HGF/c‐MET signaling in tumor cell migration

28 Apr 2010

Abstract excerpt

Deregulated hepatocyte growth factor (HGF)/c-MET axis has been correlated with poor clinical outcome and drug resistance in many human cancers. Identification of novel regulatory mechanisms influencing HGF/c-MET signaling may therefore be necessary to develop more effective cancer therapies. In our study, we show that multiple human cancer tissues and cells express filamin A (FLNA), a large cytoskeletal...

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PMID: 20473907
DOI: 10.1002/ijc.25417

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Filamin a mediates HGF/c‐MET signaling in tumor cell migrationPMID 20473907Read ↗

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