Article
Polymorphisms in the macrophage migration inhibitory factor gene and bone loss in postmenopausal women.
Bone - 1 Aug 2010
Swanberg Maria, McGuigan Fiona, Ivaska Kaisa K, Gerdhem Paul, Lerner Ulf H, Bucala Richard, Kuchel George, Kenny Anne, Akesson Kristina
Abstract excerpt
Osteoporosis is a severe condition in postmenopausal women and a common cause of fracture. Osteoporosis is a complex disease with a strong genetic impact, but susceptibility is determined by many genes with modest effects and environmental factors. Only a handful of genes consistently associated with osteoporosis have been identified so far. Inflammation affects bone metabolism by interfering with the interplay...
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