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Article

The effect of interleukin-1alpha polymorphisms on bone mineral density and the risk of vertebral fractures.

Calcified tissue international - 1 Jan 2007

Knudsen S, Harsløf T, Husted L B, Carstens M, Stenkjaer L, Langdahl B L

Abstract excerpt

Interleukin-1alpha (IL-1alpha) stimulates bone resorption via osteoclasts. Mononuclear cells from patients with osteoporosis show increased IL-1alpha production, and IL-1alpha mRNA is more often detected in bone biopsies from osteoporotic compared to normal postmenopausal women. Polymorphisms have been identified in the IL-1alpha gene; however, none of these has been examined for an effect on bone phenotypes in...

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Identifiers

PMID: 17205326
DOI: 10.1007/s00223-006-0059-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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