Article
Large scale physiological readjustment during growth enables rapid, comprehensive and inexpensive systems analysis.
BMC systems biology - 14 May 2010
Facciotti Marc T, Pang Wyming L, Lo Fang-yin, Whitehead Kenia, Koide Tie, Masumura Ken-ichi, Pan Min, Kaur Amardeep, Larsen David J, Reiss David J, Hoang Linh, Kalisiak Ewa, Northen Trent, Trauger Sunia A, Siuzdak Gary, Baliga Nitin S
Abstract excerpt
BACKGROUND: Rapidly characterizing the operational interrelationships among all genes in a given organism is a critical bottleneck to significantly advancing our understanding of thousands of newly sequenced microbial and eukaryotic species. While evolving technologies for global profiling of transcripts, proteins, and metabolites are making it possible to comprehensively survey cellular physiology in newly...
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