Article
An evolutionarily conserved RNase-based mechanism for repression of transcriptional positive autoregulation.
Molecular microbiology - 1 Apr 2014
Wurtmann Elisabeth J, Ratushny Alexander V, Pan Min, Beer Karlyn D, Aitchison John D, Baliga Nitin S
Abstract excerpt
It is known that environmental context influences the degree of regulation at the transcriptional and post-transcriptional levels. However, the principles governing the differential usage and interplay of regulation at these two levels are not clear. Here, we show that the integration of transcriptional and post-transcriptional regulatory mechanisms in a characteristic network motif drives efficient...
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