Article
Mechanism for microbial population collapse in a fluctuating resource environment.
Molecular systems biology - 20 Mar 2017
Turkarslan Serdar, Raman Arjun V, Thompson Anne W, Arens Christina E, Gillespie Mark A, von Netzer Frederick, Hillesland Kristina L, Stolyar Sergey, López García de Lomana Adrian, Reiss David J, Gorman-Lewis Drew, Zane Grant M, Ranish Jeffrey A, Wall Judy D, Stahl David A, Baliga Nitin S
Abstract excerpt
Managing trade-offs through gene regulation is believed to confer resilience to a microbial community in a fluctuating resource environment. To investigate this hypothesis, we imposed a fluctuating environment that required the sulfate-reducer Desulfovibrio vulgaris to undergo repeated ecologically relevant shifts between retaining metabolic independence (active capacity for sulfate respiration) and becoming...
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