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Article

CRF2 null mutation increases sensitivity to isolation rearing effects on locomotor activity in mice.

Neuropeptides - 1 Aug 2010

Gresack Jodi, Powell Susan, Geyer Mark, Poore Mary-Stenzel, Coste Sarah, Risbrough Victoria

Abstract excerpt

BACKGROUND: Developmental stressors are consistently reported to increase risk for certain neuropsychiatric disorders including schizophrenia, depression, and post-traumatic stress disorder. Recent clinical evidence supports a "double-hit" hypothesis of genetic vulnerability interacting with developmental challenges to modulate this risk. Early life stressor effects on behavior may be modulated in part by...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20466421
DOI: 10.1016/j.npep.2010.04.005
PMCID: PMC2888500

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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